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. Author manuscript; available in PMC: 2013 Sep 9.
Published in final edited form as: Lab Chip. 2010 Oct 27;11(2):274–281. doi: 10.1039/c0lc00157k

Figure 1.

Figure 1

Design schematic of the microfluidic approach to temperature-controlled single-molecule studies. (a) A temperature-controlled microfluidic flow cell coupled to a prism-based TIRF microscope. (b) Design layout of microheaters and temperature sensors on the coverslip.