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. 2013 Aug 19;11(8):2982–2999. doi: 10.3390/md11082982

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© 2013 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Effect of fucoidan on the levels of extrinsic and intrinsic apoptosis pathways-related proteins. (A) DR-5 and cleaved caspase-8 levels were examined by Western blot; (B) Data represent the percentage of DR5 and cleaved caspase-8 expressions in PC-3 cells; (C) Lysates were analyzed for the expression of Bcl-2, Bax, cleaved caspase-9, procaspase-3 and cleaved PARP by Western blot; (D) Data represent the percentage of Bcl-2, Bax, cleaved caspase-9, procaspase-3 and cleaved PARP expressions in PC-3 cells. Data are presented as mean ± SD from three independent experiments. * p < 0.01, ** p < 0.05, and *** p < 0.001 compared with the control (control; without fucoidan).