Table 3.
Summary of genotype and frequency observed in Korean isolates of B. pertussis
| Gene | No. reported genotypes | No. confirmed genotypes | Type and frequency (%) |
|---|---|---|---|
| Housekeeping genes | |||
| Adk | 2 | 2 | Type 1 (96.7), type 2 (3.3) |
| Fum C | 1 | 1 | Type 1 (100) |
| Gly A | 1 | 1 | Type 1 (100) |
| Tyr B | 2 | 2 | Type 1 (9.8), type 3 (90.2) |
| Icd | 1 | 1 | Type 1 (100) |
| Pep A | 1 | 1 | Type 1 (100) |
| Pgm | 1 | 1 | Type 1 (100) |
| Antigenic determinant genes | |||
| PtxS1 | 8 | 5 | Type 1 (93.2), type 2 (1.4), type 4 (1.4), type 5 (2.7%), type 8 (1.4) |
| Prn | 11 | 2 | Type 1 (96.7), type 6 (3.3) |
| Fha | 2 | 2 | Type 1 (96.7), type 2 (3.3) |
| Fim2 | 2 | 1 | Type 1 (100) |
| Fim3 | 5 | 2 | Type 1 (21.3), type 2 (78.7) |
| Omp Q | 2 | 2 | Type 1 (3.3), type 2 (96.7) |
| Bap C | 2 | 2 | Type 1 (96.7), type 2 (3.3) |
| Cya A | 2 | 2 | Type 1 (3.3), type 2 (96.7) |
| Vag 8 | 2 | 2 | Type 1 (3.3), type 2 (96.7) |
| Tcf A | 9 | 2 | Type 1 (3.3), type 2 (96.7) |
Adk, adenylate kinase; fumC, fumarate hydratase class II, glyA, serine hydroxymethyltransferase; tyrB, aromatic amino-acid aminotransferase; icd, isocitrate dehydrogenase; pepA, cytosol aminopeptidase; pgm, phosphoglucomutase; ptxS1, pertussis toxin; prn, pertactin; fha, filamentous hemagglutinin; fim2, fimbriae2; fim3, fimbriae3; ompQ, outer-membrane protein Q; bapC, Bordetella autotransporter protein C; cyaA, adenylate cyclase toxin; vag8, virulence-activated gene; tcfA, tracheal colonizing factor.