Table 5.

Summary of anatomic foci showing brain activity of tactile stimulation and positive and negative bold responses associated with the intensity of individual needling sensation (P < 0.05 corrected).

Atlas structure at the center of maximum difference		Mean fmri response to tactile				Pressure				Heaviness				Fullness				Tingling
		x	y	z	t*	x	y	z	t*	x	y	z	t*	x	y	z	t*	x	y	z	t*
Inferior frontal gyrus	L									−53	14	24	−4.01	−53	14	24	−4.01
	R					56	−2	12	3.37									41	8	12	3.02
Superior frontal gyrus	L									−11	62	21	−2.91	−11	62	21	−2.91
	R	20	−2	63	−3.20
Precentral gyrus	L	−20	−26	63	−2.86	−56	5	24	4.64
	R	35	−26	48	−2.78	56	−5	24	3.44	35	−26	51	−3.05	35	−26	51	−3.05
Orbital gyri	R	14	47	−10	−3.29
Central sulcus	L	−38	−29	57	−3.20
	R	38	−20	42	−4.55	56	−5	24	3.44	32	−26	51	−3.02	32	−26	51	−3.02
Postcentral gyrus	L	−38	−29	57	−3.20	−59	−17	30	3.46
	R	47	−17	45	−3.01	50	−17	48	3.63
Postcentral sulcus	L	−56	−23	30	3.31	−56	−20	30	4.03
	R	26	−38	57	−3.30	53	−20	36	3.00
Supramarginal gyrus	L	−62	−26	24	3.71	−56	−23	30	3.72
	R					56	−29	27	3.36
Inf. insula	L	−32	−23	9	3.20	−35	−23	9	3.79
Ant. insula	R	29	23	6	−3.71	32	26	6	3.08									29	23	6	3.08
Sup. insula	R	35	−14	21	−3.53	35	8	15	3.02									38	11	15	3.55
Superior temporal gyrus	L	−47	8	−19	−3.62	−50	8	−4	3.55	−62	−26	12	−3.19	−62	−26	12	−3.19
	R	59	−8	−1	−5.02	65	−32	15	3.18	62	−8	6	−3.33	62	−8	6	−3.33
Superior temporal sulcus	L	−47	5	−19	−3.99					−47	−35	−1	−4.53	−47	−35	−1	−4.53
	R	59	−11	−1	−4.84
Middle temporal gyrus	L	−47	8	−22	−3.52
	R	44	2	−25	−3.68
Parahippocampal gyrus	L									−20	−29	−16	3.01	−20	−29	−16	3.01	−20	−14	−25	5.48
	L	−32	−17	−22	−2.95					−14	−41	−4	−3.00	−14	−41	−4	−3.00	−32	−11	−31	−4.28
Hippocampus	R	32	−26	−13	−5.38													29	−26	−13	3.86
Lingual gyrus	L	−2	−83	−7	−3.02					−8	−74	6	−3.96	−8	−74	6	−3.96
Temporal pole	L	−47	5	−28	−3.07					−20	8	−31	−8.18	−20	8	−31	−8.18	−32	−8	−31	−5.31
	R	47	11	−25	−3.06	41	−2	−34	2.77
Cerebellum cortex	L									−8	−77	−31	3.38	−8	−77	−31	3.38
	L	−2	−53	−31	−3.08					−32	−47	−52	−3.95	−32	−47	−52	−3.95
	R	2	−50	−31	−3.26	35	−53	−52	4.07
Brain stem						−5	−29	−22	3.28

t* is the value taken from the voxel with maximal signal change.

“−” means negative bold responses.

Inf. insula: inferior segment of the circular sulcus of the insula.

Ant. insula: anterior segment of the circular sulcus of the insula.

Sup. insula: superior segment of the circular sulcus of the insula.