Table 2.
Effect of DYSGT on body weight, blood pressure, and plasma biomarker levels in ApoE KO mice.
| Parameter | |||||||
|---|---|---|---|---|---|---|---|
| Body weight (g) | Systolic blood pressure (mmHg) | BUN | LDL cholesterol | TG | |||
| Start | Final | Start | Final | (mg/dL) | (μg/μL) | (mg/dL) | |
| Cont. | 23.09 ± 0.90 | 28.58 ± 0.98 | 103.92 ± 2.00 | 105.42 ± 1.80 | 0.67 ± 0.05 | 0.19 ± 0.02 | 44.92 ± 4.81 |
| ApoE KO | 22.76 ± 0.83 | 37.18 ± 0.88** | 103.08 ± 2.69 | 118.92 ± 2.26** | 1.32 ± 0.05* | 1.02 ± 0.06** | 102.42 ± 6.67** |
| Ros. | 21.96 ± 0.44 | 35.3 ± 0.87 | 100.92 ± 2.04 | 105.58 ± 1.69## | 0.60 ± 0.03# | 0.84 ± 0.04# | 51.75 ± 5.38## |
| DYSGT | 21.92 ± 0.66 | 35.17 ± 1.32 | 100.33 ± 3.35 | 106.25 ± 2.52## | 0.70 ± 0.04# | 0.86 ± 0.03# | 47.83 ± 5.55## |
Data are mean ± SE values (n = 12); *P < 0.05, **P < 0.01 versus control; # P < 0.05, ## P < 0.01 versus ApoE KO. Cont.: control; ApoE KO: apolipoprotein E knockout; Ros: rosiglitazone; DYSGT: Doinseunggitang.