OV/TV algorithm. On the left diagram, the black solid line represents the surface of the titanium implant. The two broken lines show the inner and outer boundaries of the ROI used for μCT OV/TV measurement (hatched area). OV/TV measures BV/TV in voxels 4, 5 and 6, eliminating the 3 voxels closest to the implant surface. On the right diagram, the grids represent the μCT voxels, with the black squares representing the implant and the gray squares representing the OV/TV ROI. In this case, voxels G1, H2, H3, I4, I5, J6, J7, K8, K9 and L0 compose the implant surface. For example, voxels C1, B1 and A1 are the voxels 4, 5 and 6 away from voxel G1. For sake of clarity, the third dimension is not shown.