Table 2. MCAR Example: Results from a hypothetical clinical trial evaluating the effect of treatment on improvement in body fat (Outcome).
| a. Results from the whole study population. | ||||
|
Outcome
|
||||
| Treatment | Y | N | ||
| • Risk Ratio=(30/40)/(20/40)=1.5 | ||||
| A | 30 | 10 | 40 | • SE(Ln(RR))=0.18 |
| B | 20 | 20 | 40 | • 95% CI =1.05,2.15 |
| 50 | 30 | 80 | • Chi-Square=5.33 P=0.02 | |
|
| ||||
|
b. Results from completers following 30% missing data from a
Missing Completely At Random Mechanism (MCAR)*.
| ||||
|
Outcome
|
||||
| Treatment | Y | N | ||
| • Risk Ratio=(21/28)/(14/28)=1.5 | ||||
| A | 21 | 7 | 28 | • SE(Ln(RR))=0.22 |
| B | 14 | 14 | 28 | • 95% CI =0.98,2.30 |
| 35 | 21 | 56 | • Chi-Square=3.73 P=0.053 | |
*Each cell from Table 2a is multiplied by 70% to obtain 30% missing data from an MCAR mechanism in Table 2b.