Skip to main content
. 2013 Sep 20;86(3):343–358.

Table 3. MAR example: Results from a hypothetical clinical trial evaluating the effect of treatment on improvement in body fat (Outcome).

a. Results from the whole study population.
Men Outcome

Treatment Y N
• Outcome in A = 225/300 = 0.75
A 225 75 300 • Outcome in B = 150/300 = 0.50
B 150 150 300 • Risk Ratio = 1.5
375 225 600

Women Outcome

Treatment Y N
• Outcome in A = 90/300 = 0.30
A 90 210 300 • Outcome in B = 60/300 = 0.20
B 60 240 300 • Risk Ratio = 1.5
150 450 600

Total Outcome

Treatment Y N • Outcome in A = 315/600 = 0.525
• Outcome in B = 210/600 = 0.35
A 315 285 600 • Risk Ratio =1.5
B 210 390 600 • 95%CI=1.31, 1.71
525 675 1200 • Mantel Haenszel RR=1.5
• 95% CI=1.33, 1.70

b. Results from completers following missing data from a Missing At Random Mechanism (MAR)*.
Men Outcome

Treatment Y N
• Outcome in A = 180/240 = 0.75
A 180 60 240 • Outcome in B = 120/240 = 0.50
B 120 120 240 • Risk Ratio = 1.5
300 180 480

Women Outcome

Treatment Y N
• Outcome in A = 81/270 = 0.30
A 81 189 270 • Outcome in B = 27/135 = 0.20
B 27 108 135 • Risk Ratio =1.5
108 360 405

Total Outcome

Treatment Y N • Outcome in A = 261/510 = 0.51
• Outcome in B = 147/375 = 0.39
A 261 249 510 • Risk Ratio = 1.31
B 147 228 375 • 95% CI=1.12, 1.52
408 477 885 • Mantel Haenszel RR=1.5
• 95% CI=1.30, 1.73

*Probabilities of missing are dependent on the combination of treatment and gender to mimic an MAR mechanism

Probability Missing for Men in Trt A = 0.20

Probability Missing for Men in Trt B = 0.20

Probability Missing for Women in Trt A = 0.10

Probability Missing for Women in Trt B = 0.55