Table 1.

Patient characteristics, resource use, and treatments (unadjusted)

Characteristics	Normal–mild kidney disease				Moderate-severe kidney disease
	Medical N=4,759	PCI	CABG	P-value	Medical N=1,459	PCI	CABG	P-value
Number	1,108	2,221	1,430		528	462	469
Demographics
Age, median (25th, 75th percentiles)	60.8 (53.2, 69.0)	57.41 (50.3, 65.5)	62.3 (54.9, 69.5)	<0.001	75.3 (68.0, 80.3)	74.9 (68.9, 79.9)	74.2 (68.8, 78.5)	0.123
Caucasian race (%)	63.8	72.3	78.1	<0.001	63.8	71.8	73.9	0.001
Female gender (%)	28.1	26.1	20.4	<0.001	54.1	58.4	42.0	<0.001
Chronic Kidney Disease
Creatinine clearance, median (25th, 75th percentiles)	91.4 (75.5, 115)	99.6 (80.0, 123)	91.2 (75.7, 113)	<0.001	42.7 (32.7, 52.5)	47.7 (39.3, 54.7)	48.0 (38.9, 54.1)	<0.001
CAD risk factors
Diabetes mellitus (%)	37.4	24.6	30.7	<0.001	37.3	27.7	27.5	0.001
Hypertension (%)	65.0	57.9	60.7	0.003	76.8	70.5	73.1	0.074
Hyperlipidemia (%)	53.0	55.3	57.2	0.107	50.5	49.7	53.0	0.570
CAD history
Congestive heart failure (%)	31.5	11.7	15.1	<0.001	44.7	22.5	26.0	<0.001
Myocardial infarction (%)	53.0	62.2	50.8	<0.001	50.7	57.5	52.4	0.083
Cerebrovascular disease (%)	13.9	7.0	9.0	<0.001	21.9	12.9	18.1	0.001
Peripheral vascular disease (%)	14.3	8.1	11.0	<0.001	23.1	13.4	18.7	<0.001
CAD severity
Number diseased vessels (%)
1	45.1	55.6	7.9	<0.001	31.4	47.6	4.6	<0.001
2	26.4	33.5	26.7		28.6	36.1	20.4
3	28.4	10.8	65.3		38.3	15.9	74.8
Left main disease (%)	2.7	0.3	17.8	<0.001	9.0	0.6	20.9	<0.001
Ejection fraction, median (25th, 75th percentiles)	52.7 (39.3, 61.9)	56.4 (47.8, 63.8)	55.1 (44.2, 63.5)	<0.001	50.0 (32.9, 60.2)	55.3 (43.7, 64.6)	52.0 (40.2, 62.5)	<0.001

PCI Percutaneous coronary intervention, CABG coronary artery bypass graft