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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Pharmacogenet Genomics. 2013 Jun;23(6):324–328. doi: 10.1097/FPC.0b013e3283607acf

Table 2.

Estimated contributions to heritability of SNP variants in Asthma and two related drug-response phenotypes. Heritability estimated using polygenic linear mixed modeling. Standard error is the error associated with the heritability estimate. Percent explained is the percentage of the published heritability estimates represented by the heritability.

Sample Size (n) Heritability (h2) Standard Error p – value Published Heritability % Explained
Asthma 2633 61.5% 16% < .001 70%–90% 68%–88%
BDR 1497 28.6% 16% 0.043 10%–40% 72%–286%
AHR 1054 51.1% 34% 0.064 40%–67% 76%–128%