Accumbens core synapses are potentiated after repeated sucrose ingestion. A–C, Spontaneous EPSCs in accumbens core neurons (n = 10 cells from 3 rats, Water; n = 10 cells from 3 rats, Sucrose) after 7 d sucrose or water training. Slices were prepared immediately after bottle removal. D, E, Evoked EPSCs in accumbens core neurons (n = 10 cells from 4 rats, Water; n = 11 cells from 5 rats, Sucrose) measured at −70, −50, −30, 0, +20, +40, and +60 mV. In F, evoked EPSCs from individual records were normalized to the current at −70 mV and averaged for water and sucrose animals as indicated. Rectification index (F) calculated as EPSC−70/EPSC+40. B–G, Data are represented as mean ± SEM and analyzed using unpaired, two-tailed t tests.