Table 5.
Change in self-report measures from baseline to post-induction.
| Variable | Baseline | Post-induction | Changea | p-value |
|---|---|---|---|---|
| Global QOL | 45.1 (26.6) | 51.4 (21.4) | 6.3 | 0.28 |
| Physical functioning | 77.2 (23.3) | 73.4 (24.9) | −3.8 | 0.50 |
| Role functioning | 44.8 (33.5) | 41.5 (30.8) | −3.3 | 0.71 |
| Emotional functioning | 70.6 (26.0) | 79.6 (20.9) | 9.0 | 0.08 |
| Cognitive functioning | 76.9 (25.3) | 74.1 (27.9) | −2.8 | 0.59 |
| Social functioning | 47.3 (35.5) | 50.8 (29.6) | 3.5 | 0.66 |
| FACT-F | 31.5 (13.1) | 33.9 (11.7) | 2.4 | 0.34 |
| Fatigue VAS | 4.6 (2.6) | 4.7 (2.6) | 0.1 | 0.91 |
| HADS anxiety | 6.2 (4.7) | 4.3 (4.4) | −1.9 | 0.03 |
| HADS depression | 5.9 (4.1) | 4.7 (3.8) | −0.8 | 0.25 |
Self-report measures are reported as mean (standard deviation) scores for all participants as there were no significant differences between age groups. QOL = Quality of life; FACT-F = Functional assessment of cancer therapy – Fatigue subscale; VAS = Visual analog scale; HADS = Hospital anxiety and depression scale.
a
Minimum clinically important differences are 10 points for QOL domains, 3 points for the FACT-F, 1.5 points for the Fatigue VAS, and 2 points for the HADS subscales.