Figure 1.
A schematic of the totally connected N-state folding model. All N unfolded states are connected, and transition to another unfolded state with a rate kuu/(N − 1), and to the folded state with a rate kuf. The folded state is connected to all unfolded states. It makes transitions to an individual unfolded state with a rate kfu/N, making the total rate of unfolding kfu.