Fig. 4.

Pulsed HDX results for three peptides from Aβ₄₂. Aggregation was done at 37 °C, with agitation at 150 rpm and in the absence (solid triangles, circles, and diamonds) or presence of Cu²⁺ (hollow triangles, circles, and diamonds). Peptic peptides 1–19 (A), 20–35 (B), and 36–42 (C) are represented by triangles, circles, and diamonds, respectively. Solid lines are fits using a simple F–W model and dashed lines are fits using a modified F–W model in Mathcad.