Table 1. Summary of Animals and Virologic Studies.

Animal	Virus	Inoculum(pfu)	Route	Euthanized(study day)	CVB3 RNA(copies/ml plasma)1	PlasmaCulture	RT-PCRCardiac Tissue2
FP42	CVB-H3	107	IV	14	4.5×107	+	-3
FP49	CVB-H3	107	IV	11	2.7×106	+	LV,RV,
FP41	CVB-H3	106	IV	14	-	-	LV,RV
FP44	CVB-H3	106	IV	14	1.0×106	+	RV
FP46	CVB-H3	106	IV	28	-	-	RA,RV
FP43	CVB-H3	107	Enteral4	14	8.1×105	+	LA
FP47	CVB-MCH	106	IV	28	5.5×104	-	-
FN16	CVB-MCH	106	IV	28	3.8×106	+	-
FN20	CVB-MCH	106	IV	28	4.0×105	+	-

1. Limit of detection approximately 10,000 copies/ml. “-“  =  not detected.

2. Viral RNA detected in tissue from chamber designated. LA =  left atrium, RA  = right atrium, LV  =  left ventricle, RV  =  right ventricle.

3. Only RV, LV, and RA tissue available from this animal.

4. See text for description.