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. 2013 Sep 9;8(9):e74151. doi: 10.1371/journal.pone.0074151

Table 2. Stepwise forward multiple regression models for PROP phenotype (threshold and bitterness intensity).

PROP phenotype Variable Overall model Parameter estimate Each step
(adj R2) (p) (sr) (p) (R2)
Threshold Gustin 0.3101 <0.001 -0.38 <0.001 0.1772
TAS2R38 -0.31 0.005 0.2890
Age 0.23 0.031 0.3435
Bitterness intensity TAS2R38 0.5516 <0.001 0.65 <0.001 0.4975
Gustin 0.26 0.004 0.5593

Independent variables for both models included: Gustin genotypes, TAS2R38 genotypes, age and gender. Only the significant variables are indicated. Adj, adjusted; sr, semipartial correlation.