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. 2013 Sep 9;8(9):e74464. doi: 10.1371/journal.pone.0074464

Figure 2. A critical role of eNOS/NO and PI3K/Akt in ephrin-A1-Fc activation of angiogenesis in HUVECs.

Figure 2

A: Cell migration assay showed that L-NAME and LY294002 inhibited ephrin-A1-stimulated migration of HUVECs (200×). B: Tube formation assay showed that L-NAME and LY294002 inhibited ephrin-A1-stimulated tube formation of HUVECs (200×). Arrowheads presented the HUVECs that stretched insufficiently. C: Quantification of A. D: Quantification of B. (*, P<0.05, n = 3).