Table 5. Epidemiological MRSA clones among patients with bloodstream infection.
ST1-SCCmecII/t127 (1) | Phenotypic resistance pattern | agr allele | Toxin gene profile | No. of strains |
ST239-SCCmecIII/t030 (22) | P,OX,CX | III | sec,seh | 1 |
P,OX,CX,CN,TOB,E,CC,RA | I | none | 8 | |
P,OX,CX,CN,TOB,E,CC,RA | I | sea | 1 | |
P,OX,CX,CN,TOB,E,CC,RA | I | sea,sei | 1 | |
P,OX,CX,CN,TOB,E,CC,RA,MUP | I | none | 1 | |
P,OX,CX,CN,TOB,E,RA | I | none | 1 | |
P,OX,CX,CN,TOB,RA | I | none | 1 | |
P,OX,CX,CN,TOB,RA | I | sea | 1 | |
P,OX,CX,CN,TOB,RA | I | sea,sei | 4 | |
P,OX,CX,CN,TOB,RA | I | seg | 1 | |
P,OX,CX,CN,TOB,RA,FD | I | none | 1 | |
P,OX,CX,CN,TOB,RA,MUP | I | sea | 1 | |
ST239-SCCmecIII/t037 (13) | P,OX,CX,E,CC | I | none | 1 |
P,OX,CX,CN,TOB,E,CC | I | sea,seh | 1 | |
P,OX,CX,CN,TOB,E,CC,SXT | I | none | 3 | |
P,OX,CX,CN,TOB,E,CC,SXT | I | sea,sei | 3 | |
P,OX,CX,CN,TOB,E,CC,SXT | NT | none | 2 | |
P,OX,CX,CN,TOB,E,CC,SXT,FD | I | none | 1 | |
P,OX,CX,CN,TOB,E,CC,SXT,FD | I | sea | 1 | |
P,OX,CX,CN,TOB,E,CC,SXT,MUP | I | none | 1 | |
ST239-SCCmecIII/t129 (1) | P,OX,CX,CN,TOB,E,CC,SXT,MUP | I | sea,seh | 1 |
ST239-SCCmecIII/t459 (3) | P,OX,CX,CN,TOB,E,CC,RA | I | none | 1 |
ST5-SCCmecII/t002 (14) | P,OX,CX,CN,TOB,E,CC,RA | I | none | 3 |
P,OX,CX,CN,TOB,E,CC | II | seb,seg,sei | 1 | |
P,OX,CX,CN,TOB,E,CC | II | sec,seg,sei,tst | 2 | |
P,OX,CX,CN,TOB,E,CC | II | seg,sei | 1 | |
P,OX,CX,CN,TOB,E,CC | II | seg,sei,tst | 4 | |
P,OX,CX,CN,TOB,E,CC | NT | sec | 1 | |
P,OX,CX,CN,TOB,E,CC,MUP | II | sec,seg,sei,tst | 2 | |
P,OX,CX,CN,TOB,E,CC,SXT,RA | II | sec,seg,sei,tst | 1 | |
P,OX,CX,E,CC | II | seb,seg,sei | 1 | |
P,OX,CX,TOB,E,CC,SXT,RA,MUP | II | sec,seg,sei,tst | 1 | |
ST5-SCCmecII/t463 (1) | P,OX,CX,CN,TOB,E,RA,FD | II | sei | 1 |
ST5-SCCmecII/t11684 (1) | P,OX,CX,CN,TOB,E,CC | II | seg,sei | 1 |
ST59-SCCmecII/t163 (1) | P,OX,CX,E,CC,RA,MUP,FD | I | seb | 1 |
ST59-SCCmecIV/t172 (1) | P,OX,CX,E,CC,MUP | I | sea,seb,seh | 1 |
ST5-SCCmecIV/t062 (1) | P,OX,CX,E,RA,MUP | II | sei | 1 |
ST5-SCCmecV/t062 (1) | P,OX,CX,CN,TOB,E,CC,MUP | II | seg,sei | 1 |
ST7-SCCmecV/t091 (1) | P,OX,CX,RA,MUP | NT | none | 1 |
ST59-SCCmecV/t437 (1) | P,OX,CX,E,CC | I | seb,pvl | 1 |
Clone, ST-SCCmec; ST, sequence type by multi-locus sequence typing; SCCmec, Staphylococcal cassette chromosome mec; spa, Staphylococcus protein A gene; agr, accessory gene regulator; NT, not-typeable.
P, penicillin (10 units); OX, oxacillin (1 μg); CX, cefoxitin (30 μg); CN, gentamicin (10 μg); TOB, tobramycin (10 μg); E, erythromycin (15 μg); CC, clindamycin (2 μg); SXT, sulfamethoxazole/trimethoprim (25 μg); RA, rifampicin (5 μg); LZD, linezolid (30 μg); MUP, mupirocin (5 μg); FD, fusidic acid (10 μg).
sea-see and seg-sej, gene encoding staphylococcal enterotoxins SEA-SEE and SEG-SEJ; eta and etb, gene encoding exfoliative toxin A and B; tst, gene encoding toxic shock syndrome toxin 1; pvl, gene encoding Panton-Valentine leukocidin; none, no detection of above toxin genes.