Figure 1. Presurgical proinflammatory IL-6, IL-8, IL-1β and TNFα plasma levels significantly correlate to the stages of CRC.

Cytokines levels were measured from plasma of control group (Ctrl) or 25 CRC patients before surgery (Total), including 13 early (I-II) and 12 advanced stage (III-IV) of disease. Values are expressed as mean ± SEM and statistics were performed using unpaired Student’s T test. P values are assumed as statistically significant at p<0.05 (*); p<0.01 (**); p<0.001 (***). ns = not significant.