Figure 2. Postsurgical IL-6 and IL-8 plasma level increases are significantly lower after laparoscopy compared to open surgery, at early stages of CRC.

Pre- (T0) and postoperative (T6–48) IL-6 and IL-8 levels levels were measured from plasma of 25 CRC patients before surgery (stage I-IV), including 13 early (stage I-II) and 12 advanced (stage III-IV) stage of disease. Values are expressed as mean ± SEM and statistics were performed using unpaired Student’s T test. P values are assumed as statistically significant at p<0.05 (*).