Table 2. Spearman partial correlation coefficients (adjusted for age) between HMW adiponectin and various metabolic risk factors in metabolically healthy and unhealthy subjects.

	Men			Women
Risk factors	Metabolically healthy n = 52	Metabolically unhealthy n = 139	Whole group n = 191	Metabolically healthy n = 99	Metabolically unhealthy n = 168	Whole group n = 267
HDL cholesterol	0.27	0.39***	0.38***	0.32**	0.51***	0.55***
Triglycerides	−0.07	−0.36***	−0.33***	−0.25**	−0.32***	−0.39***
Waist circumference	−0.09	−0.30**	−0.29***	−0.16	−0.34***	−0.38***
BMI	−0.18	−0.38***	−0.34***	−0.14	−0.28**	−0.33***
HOMA-IR	−0.22	−0.44***	−0.40***	−0.27**	−0.38***	−0.42***
Fasting insulin	−0.21	−0.44***	−0.40***	−0.31**	−0.35***	−0.40***
Fasting glucose	−0.08	−0.15	−0.16*	−0.03	−0.27**	−0.28***
2h glucose in OGTT	−0.1	−0.07	−0.05	−0.17°	−0.20*	−0.27***
Systolic blood pressure	0.32*	0.06	0.05	0.04	−0.19*	−0.26***
Diastolic blood pressure	0.2	0.0006	−0.02	−0.10	−0.09	−0.23**

P<0.05 presented „bold“,°p<0.1; *p<0.05; **p<0.01; ***p<0.001

HDL – high-density lipoprotein, BMI– body mass index, HOMA-IR – homeostasis model of insulin resistance, OGTT – oral glucose tolerance test.

Healthy – subjects without impaired glucose regulation, hypertension (blood pressure ≥130/80 mmHg), dyslipidaemia (triglycerides ≥1.7 mmol/L or HDL<1.03 in men or HDL<1.3 in women) and insulin resistance.

Unhealthy – subjects with impaired glucose regulation and/or hypertension and/or dyslipidaemia and/or insulin resistance.

Insulin resistance – was defined as the upper quartile of HOMA-IR in the whole study group (exempting subjects with previously known diabetes mellitus), the threshold of which in whole study group was found to be 1.92 (2.04 and 1.82 for men and women, resp.).