Table 3. Comparison of metabolically healthy and unhealthy subjects.
Men | Women | |||||
Characteristics | Healthy n = 52 | Unhealthy n = 139 | p-value | Healthy n = 99 | Unhealthy n = 168 | p-value |
HMW adiponectin (μg/ml)* | 2.732 (1.784−3.683) | 2.436 (1.442−3.941) | 0.4 | 5.357 (3.606−6.722) | 4.146 (2.421−5.795) | 0.002 |
HOMA-IR* | 0.525 (0.440−0.908) | 1.510 (0.760−2.760) | 0.0001 | 0.670 (0.450−1.105) | 1.560 (0.885−2.715) | 0.0001 |
Waist circumference (cm) ° | 89.1±11.2 | 100.9±13.1 | 0.0001 | 81.1±11.1 | 95.9±16.1 | 0.0001 |
BMI (kg/m2) ° | 25.1±4.5 | 28.9±5.1 | 0.0001 | 24.8±4.4 | 30.8±6.9 | 0.0001 |
Age (years) ° | 38.2±13.1 | 50.9±13.5 | 0.0001 | 41.3±13.1 | 53.5±13.7 | 0.0001 |
Data presented as median (interquartile range) * or mean (±SD) °.
Healthy – subjects without impaired glucose regulation, hypertension (blood pressure ≥130/80 mmHg), dyslipidaemia (triglycerides ≥1.7 mmol/L or HDL<1.03 in men or HDL<1.3 in women) and insulin resistance.
Unhealthy – subjects with impaired glucose regulation and/or hypertension and/or dyslipidaemia and/or insulin resistance.
Insulin resistance – was defined as the upper quartile of HOMA-IR in the whole study group (exempting subjects with previously known diabetes mellitus), the threshold of which in whole study group was found to be 1.92 (2.04 and 1.82 for men and women, resp.).