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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2013 Feb 5;2(5):647–670. doi: 10.1002/wdev.108

Figure 6. A diagram depicting the actions of translational regulatory proteins on GluRIIA, GluRIIB, and eIF-4E mRNAs.

Figure 6

GluRIIA is repressed by Pum, miR-284a, and dFMR1. However, only Pum has been shown to directly bind to the 3′UTR of GluRIIA mRNA. Pum also binds to eIF-4E and nos mRNAs. GluRIIB expression is repressed by Nos, miR-284a and dFMR1. GluRIIA and GluRIIB compete for synaptic occupancy, so that GluRIIA represses GluRIIB expression and vice versa.