Table 4.
Simple effect comparisons of LGI between SBM and TD groups
| Cortical region | Left hemisphere |
Right hemisphere |
||||
|---|---|---|---|---|---|---|
| SBM | TD | p | SBM | TD | p | |
| Temporal lobe | ||||||
| Bank of STS | 3.79 (0.41) | 3.47 (0.30) | <0.001 | 4.18 (0.45) | 3.59 (0.32) | <0.001 |
| Entorhinal | 2.28 (0.16) | 2.41 (0.11) | <0.001 | 2.31 (0.17) | 2.38 (0.15) | 0.069 |
| Fusiform | 2.37 (0.19) | 2.45 (0.12) | 0.048 | 2.41 (0.16) | 2.43 (0.13) | 0.554 |
| Inferior temporal | 2.64 (0.20) | 2.52 (0.11) | 0.008 | 2.67 (0.17) | 2.43 (0.11) | <0.001 |
| Middle temporal | 3.26 (0.34) | 3.24 (0.23) | 0.760 | 3.49 (0.33) | 3.18 (0.20) | <0.001 |
| Parahippocampal | 2.31 (0.25) | 2.54 (0.17) | <0.001 | 2.40 (0.20) | 2.53 (0.20) | 0.010 |
| Superior temporal | 3.83 (0.32) | 4.13 (0.33) | <0.001 | 3.89 (0.36) | 4.07 (0.26) | 0.019 |
| Temporal pole | 2.28 (0.17) | 2.32 (0.13) | 0.322 | 2.29 (0.16) | 2.30 (0.14) | 0.787 |
| Tranverse temporal | 4.50 (0.38) | 4.78 (0.50) | 0.006 | 4.51 (0.42) | 4.77 (0.35) | 0.007 |
| Occipital lobe | ||||||
| Cuneus | 2.39 (0.29) | 2.78 (0.22) | <0.001 | 2.48 (0.30) | 2.99 (0.24) | <0.001 |
| Lateral occipital | 2.39 (0.19) | 2.44 (0.15) | 0.178 | 2.43 (0.18) | 2.52 (0.16) | 0.048 |
| Lingual | 2.33 (0.30) | 2.59 (0.18) | <0.001 | 2.46 (0.28) | 2.71 (0.21) | <0.001 |
| Pericalcarine | 2.37 (0.30) | 2.67 (0.21) | <0.001 | 2.48 (0.31) | 2.86 (0.23) | <0.001 |
| Cortical region | SBM | TD | p | |||
| Frontal lobe | ||||||
| Caudal middle frontal | 3.43 (0.27) | 3.24 (0.22) | 0.002 | |||
| Frontal pole | 1.84 (0.10) | 1.92 (0.10) | 0.002 | |||
| Lateral orbitofrontal | 2.34 (0.18) | 2.60 (0.14) | <0.001 | |||
| Medial orbitofrontal | 1.99 (0.12) | 2.00 (0.09) | 0.778 | |||
| Parsopercularis | 3.90 (0.32) | 4.29 (0.32) | <0.001 | |||
| Parsorbitalis | 2.73 (0.25) | 3.00 (0.28) | <0.001 | |||
| Parstriagularis | 3.41 (0.31) | 3.75 (0.30) | <0.001 | |||
| Precentral | 3.58 (0.24) | 3.59 (0.25) | 0.761 | |||
| Rostral middle frontal | 2.90 (0.17) | 2.73 (0.18) | <0.001 | |||
| Superior frontal | 2.22 (0.14) | 2.18 (0.12) | 0.221 | |||
| Parietal lobe | ||||||
| Inferior parietal | 3.41 (0.24) | 3.23 (0.21) | 0.001 | |||
| Paracentral | 2.24 (0.18) | 2.37 (0.17) | 0.002 | |||
| Postcentral | 3.66 (0.26) | 3.62 (0.25) | 0.485 | |||
| Precuneus | 2.54 (0.27) | 2.90 (0.22) | <0.001 | |||
| Superior parietal | 2.82 (0.18) | 3.01 (0.20) | <0.001 | |||
| Supramarginal | 4.15 (0.35) | 3.67 (0.24) | <0.001 | |||
| Cingulate cortex | ||||||
| Caudal anterior | 1.97 (0.18) | 1.90 (0.11) | 0.042 | |||
| Isthmus | 2.47 (0.28) | 2.70 (0.19) | <0.001 | |||
| Posterior | 2.16 (0.21) | 2.21 (0.16) | 0.351 | |||
| Rostral anterior | 2.04 (0.16) | 2.00 (0.11) | 0.244 | |||
Note. Values are mean (SD) LGI. The higher mean between the 2 groups, and p < 0.05, are in bold.
LGI, 3D local gyrification index; SBM, spina bifida myelomeningocele; STS, superior temporal sulcus; TD, typically developing.