Table 1.
Microbiology of 108 patients with VAD infections.
| Microorganism | N (% of total 209 isolates) | Driveline (n) | Pocket (n) | * BSI (n) | ^ IE (n) |
|---|---|---|---|---|---|
| Bacterial isolates | 178 (85.2%) | 62 | 49 | 53 | 14 |
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| Staphylococcus aureus | 44 (21.1%) | 16 | 11 | 13 | 4 |
| α MRSA | 23 (11%) | 7 | 7 | 8 | 1 |
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| Coagulase-negative staphylococci | 40 (19.1%) | 14 | 8 | 15 | 3 |
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| Enterococcus species | 30 (14.4%) | 5 | 12 | 12 | 1 |
| β VRE | 19 (9.1%) | 1 | 10 | 8 | |
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| Streptococcus viridans | 3 (1.4%) | 1 | 2 | ||
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| Corynebacterium species | 2 (1%) | 1 | 1 | ||
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| Diptheroids | 1 (0.5%) | 1 | |||
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| Bacillus species | 1 (0.5%) | 1 | |||
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| Lactobacillus species | 1 (0.5%) | 1 | |||
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| Pseudomonas aeruginosa | 21 (10%) | 11 | 3 | 5 | 2 |
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| Klebsiella pneumoniae | 9 (4.3%) | 2 | 3 | 3 | 1 |
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| Enterobacter cloacae | 7 (3.3%) | 3 | 2 | 2 | |
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| Citrobacter freundi | 4 (1.9%) | 1 | 2 | 1 | |
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| Serratia marsescens | 4 (1.9%) | 1 | 1 | 2 | |
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| Proteus mirabilis | 2 (1%) | 1 | 1 | ||
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| Escherichia coli | 1 (0.5%) | 1 | |||
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| Bacteroides species | 6 (2.9%) | 3 | 2 | 1 | |
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| Eikinella species | 1 (0.5%) | 1 | |||
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| Prevotella species | 1 (0.5%) | 1 | |||
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| Fungal isolates | 31 (14.8%) | 5 | 6 | 15 | 5 |
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| Candida albicans | 14 (6.7%) | 3 | 3 | 5 | 3 |
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| Candida glabrata | 7 (3.3%) | 2 | 4 | 1 | |
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| Candida kruseii | 6 (2.9%) | 2 | 1 | 2 | 1 |
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| Candida parapsilosis | 3 (1.4%) | 3 | |||
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| § Candida antigen + | 1 (0.5%) | 1 | |||
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| Total no. of isolates | 209 | 67 | 55 | 68 | 19 |
*
BSI is bloodstream infection
^
IE is infective endocarditis
α
MRSA is methicillin-resistant S. aureus
β
VRE is vancomycin-resistant Enterococcus species.
§
This refers to a positive serum latex agglutination test of circulating antigen in patients with systemic infection due to Candida albicans, C. tropicalis and C. parapsilosis.
A single patient may have a positive culture from more than one site.
23 patients had polymicrobial infections.
6 patients were culture negative.