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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Synth Commun. 2013 Jul 25;43(21):2906–2912. doi: 10.1080/00397911.2012.749990

Table 1.

Evaluation of the Catalytic Activities of PPTS Lipid Analogues (Figure 1) using an Esterification Reaction of 4-Phenylbutyric Acid with 1-Octanola

graphic file with name nihms482982t1.jpg
entry catalyst yield of ester (%)b
1 PPTS (1) n.d.c
2 2 n.d.
3 3 16
4 4 48
5 5 49
6 6 76/99d
7 7 n.d.
8 8 n.d.
9 9 n.d.
a

Conditions: 4-phenylbutyric acid (2 mmol), 1-octanol (2 mmol), and catalyst (5 mol%) in isooctane (4 mL) at 25 °C for 72 h.

b

Determined by GC analysis.

c

Not detected by GC experiments.

d

The yield of 76% at 25 °C and 99% at 80 °C, respectively.