Table 1.
| ||
---|---|---|
entry | catalyst | yield of ester (%)b |
1 | PPTS (1) | n.d.c |
2 | 2 | n.d. |
3 | 3 | 16 |
4 | 4 | 48 |
5 | 5 | 49 |
6 | 6 | 76/99d |
7 | 7 | n.d. |
8 | 8 | n.d. |
9 | 9 | n.d. |
Conditions: 4-phenylbutyric acid (2 mmol), 1-octanol (2 mmol), and catalyst (5 mol%) in isooctane (4 mL) at 25 °C for 72 h.
Determined by GC analysis.
Not detected by GC experiments.
The yield of 76% at 25 °C and 99% at 80 °C, respectively.