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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Synth Commun. 2013 Jul 25;43(21):2906–2912. doi: 10.1080/00397911.2012.749990

Table 2.

Syntheses of Esters Listed in Figure 2 under 6a

entry RCOOR’
12
GC yield
of ester
(%)
isolated
yield of
ester (%)
reaction condition
1 12a 99 95 catalyst 1 mol%, 80 °C, 5 h
2 12b 97 83 catalyst 1 mol%, 80 °C, 6 h
3 12c 70 61 catalyst 1 mol%, 80 °C, 30 h
4 12d 78 76 catalyst 5 mol%, 25 °C, 24 h
5 12e 99 93 catalyst 1 mol%, reflux, 16 h
6 12f 81 81 catalyst 1 mol%, 2 eq. acid, reflux, 30 h
7 12g 92 83 catalyst 1 mol%, 2 eq. acid, reflux, 48 h
8 12h 55 59 catalyst 10 mol%, reflux, 96 h
9 12i 61 50 catalyst 1 mol%, reflux, 48 h
10 12j 40 33 catalyst 10 mol%, reflux, 144 h
11 12k 99 93 catalyst 1 mol%, reflux, 96 h
12 12l 74 64 catalyst 10 mol%, reflux, 40 h
13 12m 84 78 catalyst 10 mol%, 2 eq. alcohol, reflux, 48 h
a

Unless otherwise noted, an acid (2 mmol), an alcohol (2 mmol) in isooctane (4 mL).