Table 1: Summary of Physiologic Changes During Pregnancy.
Cardiovascular | Increased uterine mass causes compression of IVC leads to venous stasis and increased risk for deep venous thrombosis,
Decreased amplitude of T-waves on electrocardiogram, Extra heart sounds / systolic S3 murmur. |
Hematologic | Hypercoagulable state leads to increased risk for thrombosis/embolism,
Leukocytosis, Physiologic anemia due to increased circulating volume, Generalized immunosuppression. |
Respiratory | Increased mucosal fragility / increased risk of airway edema, epistaxis with manipulation of nasal airway,
Decreased PaO2 while supine leads to increased risk of hypoxia, decreased functional residual capacity,progesterone-induced hyperventilation. |
Gastrointestinal | Loss of lower esophageal sphincter tone leads to increased risk of reflux disease,
Decreased gastric motility, Increased intragastric pressure. |
Genitourinary | Loss of intravascular protein causes decreased oncotic pressure leads to peripheral edema,
Increased glomerular filtration rate Urinary stasis leads to increased risk of urinary tract infections. |
Endocrine | Increase in Estrogen ,progesterone, thyroxine, steroids, insulin levels and increase in the circulating 1,25, dihydroxy-cholecaliciferol. |