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Molecular action of NBCn1. Possible molecular mechanisms by which an electroneutral NCBT could operate with an apparent Na+:HCO3− stoichiometry of 1:1. NBCn1 also exhibits a HCO3−-independent conductance that is represented by the red dashed arrow. Note that we have not included any models that are based on CO3/H cotransport, such as those represented for NBCe1 in FIGURE 16.
