Table 3.

Univariate analysis evaluating baseline patient characteristics

Characteristic	No. of patients	Median OS, years	Hazard ratio (95% CI)	P
RRM1 expression:
high	42	2.1	0.94	0.81
low	42	2.0	(0.57, 1.54)
Age, years:
< 70	43	5.4	2.19	0.002
≥ 70	41	1.3	(1.32, 3.63)
Gender:
male	63	2.0	0.95	0.86
female	21	2.0	(0.55, 1.66)
T stage:
T2	28	4.0	0.68 (0.40, 1.15)	0.15
T3	36	1.4	1.11 (0.67, 1.84)	0.68
T4	20	1.2	1.46 (0.82, 2.57)	0.2
Nodal involvement:
positive	26	1.8	0.89	0.66
negative	58	2.3	(0.52, 1.51)
Stage group
II	25	4.3	0.62 (0.36, 1.08)	0.091
III	32	1.2	1.34 (0.80, 2.23)	0.26
IV	27	1.8	1.20 (0.71, 2.02)	0.51