Figure 2.

Fusion genes validated in the primary tumour and lymph node metastasis. The top three fusions involve either an androgen-related gene, a tumour suppressor or an oncogene. The bottom five fusions involve genes with a neuroendocrine function. Note that despite absence of RNA-Seq reads (ie expression) for some fusion genes, the underlying genomic breakpoints for each fusion were detected in both primary and metastatic tumours (see Supporting information, Figure S4).