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. Author manuscript; available in PMC: 2013 Sep 10.
Published in final edited form as: J Pharmacol Exp Ther. 2008 Mar 26;326(1):1–11. doi: 10.1124/jpet.107.135830

Figure 2. Inhibition of Ras prenylation in MPNST cells by FTI/lovastatin combination treatment.

Figure 2

NF90-8 and ST88-14 cultures were treated as indicated for 24 hours. Whole cell lysates were probed for Ras prenylation status by monitoring changes in mobility via western analysis. Prenylated Ras forms migrate faster on SDS gels. FTI/lovastatin combination treatment reduced the expression of modified Ras in both cell lines. Results shown are representative of two independent experiments.