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. Author manuscript; available in PMC: 2013 Sep 10.
Published in final edited form as: J Pharmacol Exp Ther. 2008 Mar 26;326(1):1–11. doi: 10.1124/jpet.107.135830

Figure 4. FTI/lovastatin combination treatment of NF90-8 cells increases G1 and apoptotic cells.

Figure 4

NF90-8 cultures were treated 24 hours after plating according to the condition in figure. Cultures were harvested after 48 hours of treatment for DNA content stained with propidium iodide. Histograms represent 104 events and the cell cycle profile was determined using MODFIT. 500 nM 1 in combination with 500 nM lovastatin increased the number of cells in G1 and greatly increased the presence of cells with sub-G1 DNA content.