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. Author manuscript; available in PMC: 2013 Sep 10.
Published in final edited form as: J Pharmacol Exp Ther. 2008 Mar 26;326(1):1–11. doi: 10.1124/jpet.107.135830

Figure 5. Reduction of pRb hyperphosphorylation in MPNST cells lines by FTI/lovastatin combination treatment.

Figure 5

ST88-14 and NF90-8 MPNST cultures were treated as indicated for 48 hours. Whole cell lysates were probed for pRb phosphorylated at serine 780 by western analysis. Blots were stripped and reprobed for total pRb and β-tubulin. Clear reduction of pRb phosphorylation was observed following treatment with FTI plus lovastatin. * Represents hyperphosphorylated pRb.