Table 1.
Echocardiography 4 Months After AAV8.UCn2 Gene Transfer
| Con (n=8) | AAV8.UCn2 (n=8) | p Value | |
|---|---|---|---|
| EDD, mm | 4.2±0.1 | 3.8±0.1 | <0.02 |
| ESD, mm | 2.5±0.2 | 1.9±0.1 | 0.02 |
| PWD, mm | 0.6±0.1 | 0.7±0.1 | 0.49 |
| IVSD, mm | 0.6±0.1 | 0.7±0.1 | 0.49 |
| VCF, circ/sec | 8.7±0.6 | 10.6±0.5 | 0.035 |
| EF, % | 79±3 | 87±1 | <0.05 |
| HR, beats/min | 563±8 | 562±8 | 0.97 |
Con, Control; EDD, LV end-diastolic dimension; EF, LV ejection fraction; ESD, LV end-systolic dimension; HR, heart rate; IVSD, interventricular wall thickness, end diastole; PWD, posterior wall thickness, end diastole; VCF, velocity of circumferential fiber shortening.
Note: Values represent means±SE; p values were determined by Student t-test (unpaired, two-tailed).