Table 1.

Antifungal activities of the essential oil of flowers of Calendula officinalis.

Isolate	Microorganisms	Origin*	Mean zone of inhibition a (mm)
			Calendula oil15 μl/disc	Nystatin 20 μg/disc
1	C. albicans	ATCC 64548	16	12
2	C. albicans	orotracheal tube	11	13
3	C. albicans	OC – HIV	26	11
4	C. albicans	VVC	18	12
5	C. albicans	VVC	15	12
6	C. albicans	VVC	15	12
7	C. albicans	Urine	27	11
8	C dubliniensis	ATCC 777	24	11
9	C. parapsilosis	ATCC 22019	20	12
10	C. parapsilosis	Onychomycosis	14	13
11	C. parapsilosis	Paronychia	30	11
12	C. parapsilosis	Blood	30	11
13	C. glabrata	ATCC 90030	15	12
14	C. glabrata	Hands colonization	23	11
15	C. glabrata	Hands colonization	28	11
16	C. tropicalis	Urine	11	13
17	C. tropicalis	Granulomatous lesion	15	12
18	C. tropicalis	Urine	21	12
19	C. tropicalis	Urine	22	11
20	C. guilliermondii	Hands colonization	25	11
21	C. guilliermondii	Hands colonization	24	11
22	C. krusei	ATCC 6258	15	12
23	Rhodotorulla sp	Hands colonization	30	11

^*Except to ATCC microorganisms all of others are human clinical isolates OC – HIV: oral candidiasis; VVC: vulvovaginal candidiasis. Mean of inhibition zone by oil of flowers Calendula officinalis: Good activity (11 -18 mm); high activity (20-27 mm); activity (28-30 mm).