Table 2.
Comparative efficacies of Zataria multiflora essential oil and itraconazole on disseminated candidiasis in normal mice (Mean±SD of CFU/0.1 gram)
| Organ | Brain | Lungs | Liver | Spleen | Kidney |
|---|---|---|---|---|---|
| Material | |||||
| Control | 69.7± 0.10 | 28.3± 0.06 | 51.3 ± 0.03 | 8.7±0.01 | 350.8±0.41 |
| Z. multiflora (30mg/kg) | 44.9±0.12 | 13±0.09 | 36.3±0.10 | 6.7 ±0.06 | 200 ±0.44 |
| Z. multiflora (48mg/kg) | 51.8±0.20 | 4.7 ±0.05 | 2.9±0.01 | 1.8 ±0.01 | 3.8±0.21 |
| Z. multiflora (64mg/kg) | 0.4±0.01 | 0.2±0.01 | 1.3±0.09 | 0.4± 0.01 | 0.7±0.03 |
| Itraconazole (200mg/kg) | 27.2±0.10 | 10.7±0.08 | 3.3±0.03 | 1.9±0.01 | 65.9±0.27 |