Table 2.

Central composite design (CCD) matrix of independent variables in with their corresponding response by experiments and predicted.

Run	A	B	C	D	Lovastatin yielda (µg g-1 DFM)
	% Moisture content	Particle size (mm)	K2HPO4 (% v/w)	Trace ion conc. (% v/w)	Experimental	Predicted
1	60	0.35	10	10	2206 ± 51	2532
2	80	0.35	10	10	1743 ± 21	1916
3	60	0.7	10	10	1721 ± 43	1736
4	80	0.7	10	10	1203 ± 34	1353
5	60	0.35	30	10	2322 ± 51	2248
6	80	0.35	30	10	1633 ± 14	1941
7	60	0.7	30	10	989 ± 54	1238
8	80	0.7	30	10	1187 ± 23	1164
9	60	0.35	10	30	2563 ± 39	2632
10	80	0.35	10	30	1539 ± 45	1681
11	60	0.7	10	30	2076 ± 44	2159
12	80	0.7	10	30	1322 ± 60	1442
13	60	0.35	30	30	2506 ± 21	2747
14	80	0.35	30	30	2075±35	2106
15	60	0.7	30	30	2187 ± 31	2061
16	80	0.7	30	30	1587 ± 22	1652
17	50	0.525	20	20	1196 ± 47	1023
18	90	0.525	20	20	263 ± 21	262
19	70	0.175	20	20	2914 ± 54	2525
20	70	0.875	20	20	1324 ± 26	1276
21	70	0.525	0	20	3071 ± 45	2751
22	70	0.525	40	20	2795 ± 37	2678
23	70	0.525	20	0	2577 ± 17	2233
24	70	0.525	20	40	2914 ± 30	2821
25	70	0.525	20	20	2593 ± 46	2472
26	70	0.525	20	20	2501 ± 19	2472
27	70	0.525	20	20	2451 ± 61	2472
28	70	0.525	20	20	2435 ± 46	2472
29	70	0.525	20	20	2435 ± 26	2472
30	70	0.525	20	20	2443 ± 43	2472

^aValues are mean ± SD of three or more determinations