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. 2010 Jun 1;41(2):333–344. doi: 10.1590/S1517-838220100002000012

Table 2.

Distribution of MICs of different antibiotics among S. aureus isolates (132 isolates)

Antibiotic Break Point* µg/ml MIC in µg/ml
<0.25 0.5 1 2 4 8 16 32 64 128 256 512
β-lactams:
a. Penicillins:
Ampicillin 0.25 17 15 13 9 14 12 14 9 13 8 6 2
Amoxycillin 0.25 24 16 6 7 15 18 10 13 9 7 6 1
Oxacillin 2 18 35 32 15 7 8 5 6 2 2 1 1
b.Cephalosporins:
Cephalexin 16 2 3 5 7 5 8 16 28 19 23 12 4
Cefuroxime 8 3 5 6 8 13 11 17 24 20 14 8 3
Cefoperazone 16 5 5 6 3 21 1 12 14 23 14 7 0
Cefotaxime 8 2 2 6 12 24 22 14 6 28 17 12 1
Cefepime 8 17 28 13 12 3 8 12 23 11 0 0 0
β-lactam β-lactamase
inhibitor combinations:
Amp/Sul** 8 8 22 17 10 16 14 6 21 10 8 0 0
Amox/Clav** 4 10 15 17 21 26 19 12 8 4 0 0 0
Aminoglycosides:
Gentamicin 4 11 18 28 32 20 8 7 5 3 0 0 0
Amikacin 16 24 30 43 24 5 3 3 0 0 0 0 0
Fluoroquinolones:
Ciprofloxacin 1 22 18 35 23 14 7 6 4 3 0 0 0
Norfloxacin 4 10 3 22 6 26 27 16 10 9 3 0 0
Ofloxacin 1 24 21 32 23 16 9 5 1 1 0 0 0
Levofloxacin 1 33 42 20 26 5 3 3 0 0 0 0 0
Gatifloxacin 0.5 68 30 29 1 2 2 0 0 0 0 0 0
Macrolides: Erythromycin 0.5 20 9 12 14 16 25 14 8 6 5 2 1
Lincosamides: Clindamycin 0.5 36 30 21 9 6 10 8 5 4 2 1 0
Tetracyclines: Tetracycline 4 2 15 10 12 5 20 18 15 10 5 7 3
Glycopeptides: Vancomycin 4 21 20 29 25 17 8 10 2 0 0 0 0
Phenicols: Chloramphenicol 8 6 8 10 19 6 25 12 16 10 8 7 5
Ansamycins: Rifampicin 1 14 25 31 26 20 9 5 2 0 0 0 0
a

Break points of different antibiotics according to CLSI (2005).