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Formulation parameters and stability data for liposomal cefepime.
| Time (h) | CefepE (mg.mL−1) | Diameter (nm) | PdI | Drug release (%) | ||||
|---|---|---|---|---|---|---|---|---|
| A | B | A | B | A | B | A | B | |
| 0 | 0.080 | 0.150 | 117 | 136 | 0.329 | 0.291 | – | – |
| 24 | 0.0014 | 0.055 | 118 | 138 | 0.318 | 0.295 | 98.25 | 63.25 |
| 48 | – | 0.0028 | – | 135 | – | 0.301 | nd | 98.10 |
| 72 | – | – | – | – | – | – | – | nd |
CeftzE: encapsulated ceftazidime; PdI: polydispersity Index; nd: not detected; Formulation A: 40mM PC, 10mM Chol, 0.04mM α-tocopherol; Formulation B: 40mM PC, 20mM Chol, 0.04mM α-tocopherol.
