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. 2012 Jun 1;43(3):959–965. doi: 10.1590/S1517-838220120003000016

Table 1.

In vitro antimicrobial activity of structures 6d–8e against selected microbial strains (MICs expressed in μg/mL and μmol/L units, respectively).

graphic file with name bjm-43-959-g001.jpg
Staphylococcus aureus Escherichia coli Candida albicans
Entry R1 R2 ATCC 6538 CNCTC 377/79 CCM 8186
μg/mL μmol/L μg/mL μmol/L μg/mL μmol/L
6d CH3 4’-F 12500 28414 195,3 444 1562,5 3552
6e C2H5 4’-F 12500 27537 781,3 1721 1562,5 3442
6f C3H7 4’-F 6250 13356 390,6 835 781,3 1670
6g C4H9 4’-F 6250 12967 390,6 810 781,3 1621
8c CH 3’-CF 6250 12757 6250 12757 195,3 399
8d C2H5 3’-CF3 12500 24804 6250 12402 195,3 388
8e C3H7 3’-CF3 6250 12066 6250 12066 97,7 189