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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Bioorg Med Chem Lett. 2013 May 29;23(15):4398–4403. doi: 10.1016/j.bmcl.2013.05.072

Figure 5.

Figure 5

The interactions of AZ-23 (A) and dovitinib (B) in the ATP-binding pocket of a Yes1 homology model in an active (DFG-in) conformation with hinge region hydrogen bonds highlighted.