Table 1. Enrollment characteristics of study participants.
| Characteristics | Partners PrEP Participants | Adherence Substudy Sites | ||||
| Total | TDF Arm | FTC/TDF Arm | Placebo Arm | Participant Not Enrolleda | ||
| n (%) or Median (IQR) | ||||||
| Individual characteristics | n = 4,747 | n = 1147 | n = 359 | n = 386 | n = 402 | n = 597 |
| Male gender | 2,962 (62%) | 608 (53%) | 196 (55%) | 203 (53%) | 209 (52%) | 349 (58%) |
| Years of education | 7 (4–10) | 6 (3–7) | 6 (3–8) | 6 (3–8) | 6 (3–8) | 6 (3–9) |
| Age in years | 33 (28–40) | 34 (30–40) | 34 (29–40) | 35 (30–40) | 34 (30–40) | 34 (28–40) |
| Placebo | 1,584 (33%) | 402 (35%) | n/a | n/a | n/a | 183 (31%) |
| Entry into the adherence study | ||||||
| Concurrent with trial enrollment | n/a | 290 (25%) | 97 (27%) | 100 (26%) | 93 (23%) | n/a |
| Months 1–6 | n/a | 182 (16%) | 62 (17%) | 56 (15%) | 64 (16%) | n/a |
| Months 7–12 | n/a | 202 (18%) | 61 (17%) | 68 (18%) | 73 (18%) | n/a |
| After month 12 | n/a | 473 (41%) | 139 (39%) | 162 (42%) | 172 (43%) | n/a |
| Partnership characteristics | ||||||
| Married | 4,635 (98%) | 1,135 (99%) | 353 (98%) | 383 (99%) | 399 (99%) | 581 (97%) |
| Living together | 4,650 (98%) | 1,129 (98%) | 353 (98%) | 382 (99%) | 394 (98%) | 585 (98%) |
| Number of years living together | 7.0 (3.0–14.0) | 8.5 (3.7–15.3) | 8.2 (3.6–15.0) | 8.0 (3.7–15.3) | 9.0 (3.8–15.9) | 7.1 (3.0–14.2) |
| Number of children in the partnership | 2 (1–4) | 2 (1–4) | 2 (1–4) | 2 (1–4) | 2 (1–4) | 2 (1–4) |
| Polygamous marriage | 974 (21%) | 282 (25%) | 82 (23%) | 104 (27%) | 96 (24%) | 158 (27%) |
| Age difference between partners | 1 (−4 to 6) | 0 (−5 to 5) | 1 (−6 to 5) | 0 (−6 to 5) | 0 (−5 to 5) | 0 (−6 to 6) |
| Unprotected sex in prior month | 1267 (28%) | 321 (29%) | 107 (30%) | 111 (30%) | 103 (26%) | 142 (25%) |
| HIV-infected partner CD4 count (cells/mm3) | 495 (375–662) | 491 (368–667) | 464 (348–626) | 503 (380–682) | 504 (372–687) | 477 (355–645) |
| HIV-infected partner viral load (log copies/ml) | 3.9 (3.2–4.5) | 4.0 (3.3–4.6) | 4.1 (3.4–4.6) | 3.9 (3.2–4.5) | 4.0 (3.4–4.6) | 4.0 (3.3–4.6) |
Complete data were available on all variables (n = 1,147) except for questions regarding unprotected sex in the prior month (missing in 3%), polygamy (<1%), and viral load (1%).
a
From the three sites from which the adherence substudy recruited.
n/a, not applicable.