Table 1.
Demographic and Clinical Characteristics of Subjects
| Variable | SHF (overall) (n = 1012) | HFPSF (overall) (n = 872) | HFPSF (QRS < 120 ms) (n = 679) | HFPSF (QRS ≥120 ms) (n = 193) |
|---|---|---|---|---|
| Age (y) | 71 ± 14 | 74 ± 13* | 72 ± 13 | 78 ± 11† |
| Gender (% female) | 41 | 67* | 69 | 60† |
| Race (% Caucasian) | 73 | 79* | 78 | 82 |
| BMI (kg/m2) | 29.0 ± 7.6 | 32.0 ± 9.4* | 32.8 ± 9.6 | 29.8 ± 8.1† |
| LVEF (%) | 25 ± 8 | 60 ± 8* | 60 ± 8 | 59 ± 7 |
| EFFECT model score (points) | 96 ± 26 | 105 ± 26† | ||
| ECG QRS duration (ms) | 89 ± 12 | 148 ± 22† | ||
| History of: Heart failure (%) | 84 | 75* | 72 | 83† |
| CAD (%) | 72 | 57* | 54 | 64† |
| Atrial fibrillation (%) | 25 | 27 | 33 | 47† |
| Hypertension (%) | 76 | 84* | 84 | 82 |
| Admit systolic BP (mm Hg) | 142 ± 33 | 154 ± 33* | 154 ± 32 | 157 ± 33 |
| Admit diastolic BP (mm Hg) | 79 ± 21 | 77 ± 20* | 77 ± 20 | 77 ± 20 |
| Admit heart rate (beats/min) | 90 ± 22 | 85 ± 22* | 86 ± 22 | 84 ± 21 |
| Peripheral edema on exam (%) | 73 | 81* | 81 | 79 |
| Radiographic pulmonary edema (%) | 67 | 70 | 69 | 74 |
| Laboratory studies at admission: | ||||
| Serum creatinine | 1.7 ± 1.4 | 1.8 ± 1.7 | 1.7 ± 1.6 | 1.8 ± 1.9 |
| Serum sodium | 137 ± 5 | 138 ± 4 | 138 ± 4 | 137 ± 4† |
| Serum hemoglobin | 12.4 ± 2.0 | 11.8 ± 2.0* | 11.9 ± 2.0 | 11.6 ± 2.0 |
BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; ECG, electrocardiogram; HFPSF, heart failure with preserved systolic function; LVEF, left ventricular ejection fraction; SHF, systolic heart failure; EFFECT, Enhanced Feedback for Effective Cardiac Treatment Score.
Continuous variables are presented as means ± SD.
*
Denotes significant (P < .05) difference between SHF and HFPSF in overall population.
†
Denotes significant (P < .05) difference between HFPSF subjects with QRS <120 ms and QRS ≥120 ms.