Table 4.
Group | Cell density (×106 cells/mL) | Deoxyribose new synthesis (1-m0)a | m5/Σm G6PDH activity (m ≠ 0) | m3/Σm transketolase activity (m ≠ 0) |
---|---|---|---|---|
A (control) | 2.34 ± 0.06 | 0.258 ± 0.010 | 0.302 ± 0.008 | 0.244 ± 0.005 |
B | 1.31 ± 0.10** | 0.269 ± 0.002 | 0.315 ± 0.001 | 0.259 ± 0.001* |
C | 1.98 ± 0.24 | 0.307 ± 0.013* | 0.274 ± 0.009* | 0.226 ± 0.000** |
D | 1.65 ± 0.17* | 0.329 ± 0.003* | 0.310 ± 0.001 | 0.258 ± 0.001* |
Data are presented as the mean ± SEM
The sum of all isotopomers equal to 1. For example, if half of the DNA is labeled during one cell division, this equals a new DNA synthesis fraction of 0.5
Significantly different when compared with control A, p <0.05
Significantly different when compared with control A, p <0.01