Figure 1. Design of the animal experiment.
Fourty C3H mice associated with a defined microbial community of 8 bacterial species (SIHUMI) were allocated to four different groups (10 mice per group). Each mouse was associated with 8 bacterial species (SIHUMI). Twelve weeks-old SIHUMI mice were subsequently associated with A. muciniphila (SIHUMI-A) or S. Typhimurium (SIHUMI-S) or with both A. muciniphila and S. Typhimurium (SIHUMI-AS). SIHUMI mice received only sterile medium. Times of association, infection and killing are as indicated. ‡ - killed.