Fig. 2.

Time course and functional classification. A, Total number of identified labeled proteins at every time point including all replicates for both controls and patients. B, Sixty-one proteins were labeled in at least one of the three secretome replicates of either of the two groups (control or patient) after 96 h in culture. Of these proteins, 50 were observed in aortic stenosis (AS) valves and 23 in control valves. The secreted and labeled proteins were classified into six different groups based on their molecular function.