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. 2013 Sep 10;8(9):e74026. doi: 10.1371/journal.pone.0074026

Figure 6. Immune response, histopathology and parasite burden of infected wild type versus IL-4Rα-/- mice.

Figure 6

Levels of IL-4 (A), IL-13 (B), IL-10 (C) and IFN-γ (D) produced by mLN cells from naïve controls and mice at day 14 post infection in response to adult worm antigen. (E) Goblet cell counts in duodenal cross sections. (F) Enteritis scores for duodenal tissue. Representative duodenum cross sections from naïve (G) and acutely infected (H) wild type and IL-4Rα-/- mice stained with H&E (upper row) and periodic acid/Schiff (lower row) for histopathological scoring and goblet cell quantification. (I) Adult worm counts of WT and IL-4Rα-/- mice at day 14 post infection. Mean + SEM of 5-6 mice per group is shown. * p < 0.05; ** p < 0.005.