Table 2. Distributions of eight single nucleotide polymorphisms, genetic predisposition score, Tanner stages of puberty, meal patterns and body mass index among adolescents in the Northern Finland Birth Cohort 1986.
| Boys (n = 2215) | Girls (n = 2449) | All (n = 4664) | ||||
| Mean BMI kg/m2 (95% CI) | % | Mean BMI kg/m2 (95% CI) | % | Mean BMI kg/m2 (95% CI) | % | |
| FTO rs1421085 | ||||||
| TT | 20.8 (20.5, 21.0) | 35.9 | 21.1 (20.8, 21.3) | 34.9 | 20.9 (20.8, 21.1) | 35.4 |
| CT | 21.1 (20.9, 21.3) | 47.9 | 21.2 (21.0, 21.4) | 48.2 | 21.2 (21.0, 21.3) | 48.0 |
| CC | 21.8 (21.4, 22.2) | 16.2 | 21.7 (21.3, 22.0) | 16.9 | 21.7 (21.5, 22.0) | 16.6 |
| MC4R rs17782313 | ||||||
| TT | 21.1 (20.9, 21.2) | 69.1 | 21.1 (20.9, 21.2) | 67.5 | 21.1 (21.0, 21.2) | 68.2 |
| CT | 21.1 (20.8, 21.4) | 27.8 | 21.5 (21.2, 21.7) | 29.2 | 21.3 (21.1, 21.5) | 28.5 |
| CC | 21.9 (21.1, 22.7) | 3.1 | 22.5 (21.6, 23.5) | 3.3 | 22.2 (21.6, 22.9) | 3.2 |
| BDNF rs6265 | ||||||
| CC | 21.0 (20.9, 21.2) | 70.1 | 21.2 (21.1, 21.4) | 70.3 | 21.1 (21.0, 21.2) | 70.2 |
| CT | 21.3 (21.0, 21.5) | 27.2 | 21.2 (21.0, 21.5) | 27.2 | 21.2 (21.1, 21.4) | 27.2 |
| TT | 21.4 (20.5, 22.4) | 2.7 | 21.3 (20.4, 22.2) | 2.5 | 21.4 (20.7, 22.0) | 2.6 |
| GNPDA2 rs10938397 | ||||||
| AA | 21.1 (20.9, 21.4) | 26.4 | 20.9 (20.7, 21.1) | 26.9 | 21.0 (20.9, 21.2) | 26.7 |
| AG | 21.0 (20.8, 21.2) | 50.0 | 21.3 (21.1, 21.5) | 48.5 | 21.2 (21.0, 21.3) | 49.2 |
| GG | 21.2 (20.9, 21.6) | 23.6 | 21.4 (21.1, 21.7) | 24.6 | 21.3 (21.1, 21.5) | 24.1 |
| MAF rs1424233 | ||||||
| CC | 21.1 (20.9, 21.4) | 32.3 | 21.0 (20.8, 21.2) | 32.0 | 21.1 (20.9, 21.2) | 32.2 |
| CT | 21.0 (20.7, 21.2) | 48.7 | 21.3 (21.1, 21.5) | 50.4 | 21.1 (21.0, 21.3) | 49.6 |
| TT | 21.5 (21.1, 21.8) | 19.0 | 21.4 (21.1, 21.8) | 17.6 | 21.5 (21.2, 21.7) | 18.2 |
| TMEM18 rs6548238 | ||||||
| TT | 20.2 (19.3, 21.2) | 2.1 | 20.5 (20.0, 21.1) | 2.5 | 20.4 (19.9, 20.9) | 2.3 |
| CT | 21.1 (20.8, 21.3) | 27.1 | 21.2 (20.9, 21.4) | 25.8 | 21.1 (20.9, 21.3) | 26.4 |
| CC | 21.2 (21.0, 21.3) | 70.8 | 21.3 (21.1, 21.4) | 71.7 | 21.2 (21.1, 21.3) | 71.2 |
| KCTD15 rs11084753 | ||||||
| AA | 21.0 (20.5, 21.4) | 12.2 | 21.1 (20.8, 21.5) | 11.2 | 21.1 (20.8, 21.4) | 11.7 |
| AG | 21.1 (20.9, 21.3) | 45.6 | 21.2 (21.0, 21.4) | 45.5 | 21.1 (21.0, 21.3) | 45.5 |
| GG | 21.1 (20.9, 21.4) | 42.2 | 21.3 (21.1, 21.5) | 43.3 | 21.2 (21.1, 21.4) | 42.8 |
| NEGR1 rs2815752 | ||||||
| GG | 20.8 (20.4, 21.1) | 13.8 | 20.9 (20.6, 21.3) | 12.3 | 20.8 (20.6, 21.1) | 13.0 |
| AG | 20.9 (20.7, 21.1) | 46.1 | 21.2 (21.0, 21.4) | 47.0 | 21.1 (20.9, 21.2) | 46.6 |
| AA | 21.5 (21.2, 21.7) | 40.1 | 21.4 (21.2, 21.6) | 40.7 | 21.4 (21.2, 21.6) | 40.4 |
| Genetic risk score <8 | 20.8 (20.6, 21.0) | 48.7 | 20.9 (20.7, 21.0) | 47.3 | 20.8 (20.7, 21.0) | 48.0 |
| Genetic risk score ≥8 | 21.4 (21.2, 21.6) | 51.3 | 21.5 (21.4, 21.7) | 52.7 | 21.5 (21.3, 21.6) | 52.0 |
| Tanner stage of puberty | ||||||
| II | 17.9 (15.7, 20.1) | 0.5 | 20.7 (18.3, 23.1) | 0.3 | 18.9 (17.3, 20.6) | 0.4 |
| III | 20.6 (20.0, 21.2) | 6.8 | 20.3 (20.0, 20.6) | 15.5 | 20.4 (20.1, 20.7) | 11.3 |
| IV | 20.6 (20.4, 20.9) | 38.1 | 21.1 (20.9, 21.2) | 57.1 | 20.9 (20.8, 21.0) | 48.1 |
| V | 21.5 (21.3, 21.7) | 54.6 | 22.1 (21.8, 22.4) | 27.1 | 21.7 (21.6, 21.9) | 40.2 |
| Meal pattern | ||||||
| Regular (five meals a day with breakfast) | 20.6 (20.4, 20.8) | 53.6 | 20.8 (20.6, 21.0) | 40.5 | 20.7 (20.6, 20.8) | 46.7 |
| Meal skipping (≤4 meals a day) | 21.7 (21.4, 21.9) | 46.4 | 21.5 (21.4, 21.7) | 59.5 | 21.6 (21.5, 21.7) | 53.3 |
Data presented as mean values (95% CIs) and percentages.
Abbreviations: BMI, body mass index; CI, confidence interval.